Biological aging clock

The Clinical Standard for Longevity

Transform standard clinical lab data into transparent, actionable roadmaps for patient health. Beyond "Black Box" DNA tests, map system-level aging patterns to identify intervention

Developed at National University of Singapore (NUS)
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MAP FOR AGING TRAJECTORIES

Scientifically validated biomarkers reveal how the body is aging and what can be improved

How we measure aging

A biological aging clock built on standard biomarkers, not DNA sampling

We turn routine lab data into a structured measure of biological aging that clinicians can interpret and treat.

01

Routine clinical data

Our LinAge2 algorithm works with blood, urine, and standardised biomarkers that clinics already collect and trust.

02

Model how systems age together

The clock looks at interactions across inflammation, metabolism, kidney function, liver stress, and other physiological domains instead of treating biomarkers in isolation.

03

Interpretable aging signals

The output is not just a number. Clinicians see biological age, confidence intervals, and the principal components driving the signal.

Take a closer look

Beyond Clock biomarker inputs screen

Routine inputs

Start with biomarker panels teams already know how to collect.

BeyondClock begins with routine blood, urine, and chemistry inputs, making the workflow easier to operationalize than specialized molecular sampling.

Beyond Clock systemic modelling screen

Systemic modelling

Model how physiological systems change together.

The model captures interactions across metabolic, inflammatory, renal, hepatic, and broader physiological domains instead of treating biomarkers as isolated signals.

Beyond Clock explainable output screen

Explainable output

Show what is driving the signal, not just the final score.

Principal components expose the biological domains behind the readout so clinicians and operators can link the result to concrete physiological change.

Beyond Clock biological age screen

Biological age

Turn biomarker patterns into a clear biological age readout.

The biological age view brings the measurement into a format teams can understand quickly, with a clear comparison against chronological age and cohort context.

Business applications

Made for organizations that need aging measurements to drive decisions

Applicable use cases for different needs

Longevity clinics
Labs
Pharma
Clinical trial teams
Longevity programs

Validate treatment decisions earlier

Use objective aging signals before and after an intervention to understand whether a program is moving people toward a healthier baseline.

Find the right trial participants faster

Screen for biological rather than chronological aging patterns when identifying who is most relevant for an intervention or cohort.

Predict likely response trajectories

Track whether participants are trending toward frailty, metabolic decline, or healthier recovery capacity as programs evolve.

Validate treatment effectiveness

Give teams a biological scoreboard for diet, supplements, health programs, or therapeutics instead of relying only on single-marker snapshots.

Measure aging at scale

Turn longevity measurement into an operational capability for population health, preventive care, corporate wellness, or member engagement.

Rooted in Credible science

Real longevity needs credible science behind it

LinAge2 is supported by a peer-reviewed paper, “LinAge2: providing actionable insights and benchmarking with epigenetic clocks”, published in npj Aging. The work tests the model against other aging-clock approaches and focuses on the things that matter operationally: mortality prediction, benchmarking, and interpretability.

npj Aging
Published April 23, 2025
PMCID: PMC12019333
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